Parental acceptance of and preferences for administration of routine varicella vaccination in the UK: A study to inform policyArticle Published on 2023-02-172023-06-01 Journal: Vaccine [Category] 두창, 수두, 홍역, [키워드] acceptance Chickenpox children parents preference Routine immunisation vaccination Vaccine hesitancy varicella. [DOI] 10.1016/j.vaccine.2023.01.027 PMC 바로가기
Patient preferences and current practice for adults with steroid-resistant ulcerative colitis: POPSTER mixed-methods studyArticle Published on 2022-10-012022-11-15 Journal: Health technology assessment (Winchester, England) [Category] 진단, [키워드] administration assessment carried Characteristics Consensus COVID-19 pandemic drug duration of symptom Effectiveness evaluate experiment experiments Factor Future greater Health personnel health-care highlight IMPROVE Inflammatory bowel disease influence information journal lack less library Necrosis NHS NIHR offered over Patient Patient preference patients per day predicted Prednisolone preference preferences Probability professional professionals qualitative research randomised controlled trial Randomised controlled trials recommendation Research respond risk sample sizes secondary care Selection bias severity Side effect Side effects subject surveys and questionnaires Symptoms technology therapeutic benefits Tofacitinib Treatment ulcerative ulcerative colitis ulcerative colitis. undergo website [DOI] 10.3310/RHXR5192 PMC 바로가기
High recurrence of lymphedema and influencing factors in discharged breast cancer patients during the COVID-19 pandemic: A multicenter, cross-sectional surveyArticle Published on 2022-10-012022-11-16 Journal: Cancer Medicine [Category] COVID19(2023년), SARS, 치료기술, [키워드] 95% confidence interval analysis Anxiety Breast cancer breast cancer patient caused Characteristics Complete conducted coronavirus disease COVID-19 COVID-19 pandemic cross-sectional cross-sectional survey Depression difference discharged effort eight elevated Factor feasible groups Guidance hospital identify increased risk information lockdown Logistic regression lymphedema management Mild moderate multicenter multivariable Multivariable regression norman Questionnaire. Odds ratio Older age Pain pandemic Patient patients performed preference Prevalence pros Psychological distress quarantine Radiotherapy reported risk self-care Self-management Symptom the patient Treatment was used while Wuhan, China [DOI] 10.1002/cam4.4737 PMC 바로가기
Transition to endemic: acceptance of additional COVID-19 vaccine doses among Canadian adults in a national cross-sectional surveyArticle Published on 2022-09-142022-11-16 Journal: BMC Public Health [Category] SARS, 변종, [키워드] analysis Annual benefit booster dose chronic conducted COVID-19 COVID-19 disease COVID-19 vaccine cross-sectional cross-sectional survey determine dose doses Effectiveness facilitate Factor Factors Government higher education higher odd identify identity immunization increasing age Infection influences on Influenza influenza vaccine Intention multinomial logistic regression National new SARS-CoV-2 Offering Pharmacy populations preference primary dose receive recommendation refusal reported required seasonal Sociodemographic targeted intervention third dose transition vaccination Vaccine vaccine dose vaccine. variants waning immunity were used widespread [DOI] 10.1186/s12889-022-14025-8 PMC 바로가기
Considering epitopes conservity in targeting SARS-CoV-2 mutations in variants: a novel immunoinformatics approach to vaccine design변이체에서 SARS-CoV-2 돌연변이 표적화에서 에피토프 보존성 고려: 백신 설계에 대한 새로운 면역정보학 접근Article Published on 2022-08-182022-09-11 Journal: Scientific Reports [Category] SARS, 변종, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus adaptive Adaptive immunity antibody antigenicity approach Avian flu calculated collected conserved Coronavirus-2 database Developing Efficacy epitope Epitopes event flu ideal identify IEDB immune Immune Epitope Database Immunity immunodominant immunogenicity immunoinformatics mutated Mutation mutations neutralization pathogenicity platform predicted preference provide reduce Region SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 genomes SARS-CoV-2 mutation selected Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus-2 Shannon entropy similarity solution technique Vaccine design Vaccines variant variants virulence virus viruses [DOI] 10.1038/s41598-022-18152-5 PMC 바로가기 [Article Type] Article
Phytochemical Discrimination, Biological Activity and Molecular Docking of Water-Soluble Inhibitors from Saussurea costus Herb against Main Protease of SARS-CoV-2SARS-CoV-2의 주요 프로테아제에 대한 Saussurea costus Herb의 수용성 억제제의 식물화학적 판별, 생물학적 활성 및 분자 도킹Article Published on 2022-08-012022-09-11 Journal: Molecules [Category] SARS, 변종, [키워드] activity andrographolide ATCC Bacterial binding affinity Bioavailability Biological biological activity carbohydrate carbohydrates carboxylic acid catalytic dyad Cell cell entry Compound coronavirus coronavirus SARS-CoV-2 costus COVID-19 Cys145 D614G variant Delta discrimination docked Escherichia coli event Fatty acid fatty acids FIVE followed by Gamma gas chromatography Gas Chromatography-Mass Spectrometry GC-MS GC-MS profiling Herb His41 HSV-1 virus inhibit inhibitor inhibitory effect investigated M pro main protease mass spectrometry medical system molecular docking molecular docking. phytochemical preference prevalent protease Protein pseudovirus ranged residue room temperature SARS-CoV-2 SARS-CoV-2 entry Saussurea Saussurea costus Siddha spike Spike proteins Staphylococcus aureus Sterol Strains tannin tannins temperature these compounds variant virucidal virus VoC water [DOI] 10.3390/molecules27154908 PMC 바로가기 [Article Type] Article
The effects of probiotics on risk and time preferences Research Published on 2022-07-152022-10-05 Journal: Scientific Reports [Category] 유전자 메커니즘, [키워드] Affect animal brain region cognitive conducted creating daily dose double-blinded Effect emotional experimental evidence functional gut microbiota healthy Human increase in Interaction investigated mechanism nervous system participant Placebo placebo-controlled preference risk separated significant decrease the placebo group two group [DOI] 10.1038/s41598-022-16251-x [Article Type] Research
Nasopharyngeal swabs vs. saliva sampling for SARS-CoV-2 detection: A cross-sectional survey of acceptability for caregivers and children after experiencing both methodsSARS-CoV-2 검출을 위한 비인두 면봉 대 타액 샘플링: 두 가지 방법을 모두 경험한 후 간병인과 어린이의 수용 가능성에 대한 횡단면 조사Article Published on 2022-07-082022-09-11 Journal: PLoS ONE [Category] COVID19(2023년), SARS, 치료기술, [키워드] 5-point Likert scale acceptability acceptance Accuracy Administered children Community Complete Consent COVID-19 testing cross-sectional survey described face Factor hypothetical Local Nasopharyngeal swab nasopharyngeal swabbing nasopharyngeal swabs Pain participant Participation preference Saliva sampling SARS-CoV-2 SARS-CoV-2 testing Swab understanding was measured Youth [DOI] 10.1371/journal.pone.0270929 PMC 바로가기 [Article Type] Article
Public support for unequal treatment of unvaccinated citizens: Evidence from DenmarkRandomized Controlled Trial Published on 2022-07-012022-10-04 Journal: Social science & medicine (1982) [Category] 임상, [키워드] changes in COVID-19 Denmark evaluate experiment General population Government hospital Isolation liberal likelihood pandemic Policy preference provide Public public health raising Randomly reduce Regulation severity significantly Spread statistically Support Treatment Trust vaccinated against COVID-19 vaccination Vaccines. virus while [DOI] 10.1016/j.socscimed.2022.115101 PMC 바로가기 [Article Type] Randomized Controlled Trial
High-throughput drug screening allowed identification of entry inhibitors specifically targeting different routes of SARS-CoV-2 Delta and Omicron/BA.1고용량 약물 스크리닝을 통해 SARS-CoV-2 Delta 및 Omicron/BA.1의 다양한 경로를 구체적으로 표적으로 하는 진입 억제제 식별 가능Article Published on 2022-07-012022-09-11 Journal: Biomedicine & pharmacotherapy = Biomédecine & phar [Category] COVID19(2023년), SARS, 변종, 신약개발, 유전자 메커니즘, [키워드] acute respiratory syndrome coronavirus Alpha antagonist antagonists applied BA.1 Beta Caco2 cells Cathepsin-L cell entry cells cellular entry chlorpromazine Combination Compound D614G Delta drug Drug repurposing Drug screening Entry inhibitor FDA-approved drugs G protein G protein coupled receptor antagonist G-protein help highest identify Infection route inhibit inhibitors lentiviral Lentiviral vector lentiviral vectors mechanism membrane fusion omicron pathway phenothiazine preference pseudotyped pseudovirus pseudovirus pseudoviruses receptor receptor antagonist Receptor binding receptors respiratory responsible resulting SARS-CoV-2 several variant several variants Severe acute respiratory syndrome specific inhibitors spike variant synergistic targets TMPRSS2 variant Variant of concern. viral entry VoC VOCs [DOI] 10.1016/j.biopha.2022.113104 PMC 바로가기 [Article Type] Article